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The Ultimate Guide to CBD

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What is CBD?

Oil drippedCBD, short for cannabidiol, is a compound that is produced by the cannabis plant. It has grown quickly in popularity and has headed toward mainstream culture’s acceptance. CBD oil is finding its place in different products from tinctures to edibles to cosmetics. CBD oil is even used by pet owners to help their animals live longer and healthier lives.

First, we need to set things straight. It’s important to note that hemp seed oil and CBD oil are not the same thing. Hemp seed oil is the oil extracted from the hemp seeds used for cooking and as a dietary supplement. The two are different in the fact that one does not have CBD or other Cannabinoids.

CBD oil has a long and colorful history. For a quarter of a century, it would seem CBD was almost non-existent. Today thanks to modern science we have identified a family of molecules that are known as “Cannabinoids” as well as how they affect the “Human Endocannabinoid System.”  We are just now scratching the surface to see how CBD oil affects the body. CBD has a lot of people asking questions and looking to become educated on this alleged cure-all.  That’s why this guide is here.

The Origins of CBD

Meditation StatueThe earliest written record that mentions the use of cannabis shows up in ancient China around 6000 B.C. This time has a direct correlation to human civilization starting to dabble in the medicinal properties of herbs. The next connection in  medical history was around 2700 B.C. Here we see cannabis being used in medicinal practice to help relieve a variety of ailments. In the year 2737 B.C. records in the “Pen Ts’ao Ching,” state that the Chinese emperor Shen-Nung was using cannabis in the form of topical ointments and teas. He did this to help facilitate pain relief.

As time progressed we leap forward to writings about the medicinal benefits of cannabis. Cannabis extracts were used as blood thinners and anesthetic in the second century B.C. writings of Hua Tuo.

Across the landscape we see Romans beginning to use hemp in 77 A.D. In the writings of scholar Pliny the Elder also claimed that cannabis extract could be used for pain relief. We see this pattern emerge from across the globe only to soon be buried with Ancient Greeks and Egyptians who formulated cannabis remedies.

History of CBD Oil in the West

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In the sixteenth century, cannabis was being cultivated all over Europe. Hemp became very valuable to society around this time. In 1533, King Henry VIII required all farmers to grow hemp. Physicians at this time specifically Garcia de Orta and Le Shih-Chen documented the use of hemp extract as a way to stimulate appetite and used it as an antibiotic. 1600s brought hemp cultivation to North America.

The American colonies were found to cultivated acres of hemp. The colony of Virginia followed Henry’s way and passed laws to require the cultivation of hemp by farmers. The colonies like Massachusetts and Connecticut did the same. They even used hemp seeds as a legal form of currency in Virginia, Pennsylvania, and Maryland.

By the eighteenth century hemp was documented in the “The New England Dispensatory” and the “Edinburgh New Dispensatory”-were two highly respected pharmacopeias of their day. Using hemp extract in dealing with different ailments medically. As the Industrial Age was beginning to sprout a surgeon by the name W.B. O’Shaughnessy started to praise the qualities of hemp remedies in the American Southwest. To expand on this as a professor at the Medical College of Calcutta, he conducted experiments with hemp extract. He conducted experiments on animals and humans who were suffering from rheumatic diseases, cholera, tetanus, and hydrophobia. His notes discuss the ability of hemp extract in relieving pain and relaxing muscle spasms.

Later a doctor by the name J.R. Reynolds was conducting experiments on the ability of hemp extract to reduce tics and help asthma. Hemp extract around this time was listed in the third edition of the U.S. Pharmacopeia as a pain reliever; sleep aid, and antidepressant prior to the end of eighteenth century when J.R. came onto the seen.

Modern Day CBD

Cannabis Chemical formulaIn the early twentieth century medicines such as opioids were in development and the use of the cannabis-based preparations in relieving pain was on the decline. However, medications that were being manufactured did have cannabis in their recipe. It was put into everything from cough syrup to sleep aids. By the late 1930s the war on cannabis began. The cultivation of cannabis became illegal. In 1970, the Controlled Substance Act banned cannabis cultivation. This listed cannabis, hemp, and marijuana as a “schedule 1 substances” that have no medicinal benefits and have a high-risk of dependence.

Today CBD oil is available to everyone and research into CBD’s effect on the body has substantially increased. The use of modern technology has provided methods of refining and isolating CBD. This increases the bioavailability of CBD oil using nano emulsions. These emulsions make CBD water-soluble and increase its potency. The projection of profits from this are said to surpass $1 billion by 2020.

Later in the 1960s is where the mysteries of the Cannabinoids, including CBD, had begun to capture researchers eye. They discovered the role of the human Endocannabinoid system in maintaining good health. This progressed in the 1970s, and cannabis extracts were being used once again for healing. Later in 1996 in the state of California, it became legal for medicinal use of cannabis for a list of serious medical conditions.

Over the past few decades, there has been an eruption of research into the health benefits that come from CBD and other cannabinoids. CBD has been quickly gained acceptance in the U.S. as a result of media coverage by health experts who are respected in their field. The message of CBD’s healing powers is beginning to reach the masses.

CBD oil today is available to everyone and research into CBD’s effect on the body has risen substantially. The use of modern technology has provided methods of refining and isolating CBD. This also increases the bioavailability of CBD oil using Nano emulsions that makes CBD water-soluble and increases the potency. The projection of profits from this are said to surpass $1 billion by 2020.

Medical Disclaimer

Before beginning, The Federal Food, Drug, and Cosmetic Act requires that we must inform you that the effectiveness of CBD oil products has not been confirmed by FDA-approved research as a treatment for any medical condition. The information in this document is not intended to diagnose, treat, cure or prevent any disease. This guide contains information that will help you make educated decisions about why and how to use CBD oil. It is not intended to provide medical advice. It’s important that the reader seek the advice of a qualified medical professional that is well versed in the therapeutic use of CBD before beginning use.

CBD Oil Basic Information

To begin we will be discussing some basic information such as what CBD oil is where it comes from and how it’s produced. We will also answer some of new CBD users’ frequently asked questions.

What is CBD Oil?

CBD oil is a natural essential oil that is extracted from the flowers and leaves of the cannabis plant. It is then used by people all over the world as a dietary supplement this is used for a variety of therapeutic purposes. CBD oil contains an array of active compounds such as cannabinoids and terpenes. It has been shown through research to be well-tolerated and non-toxic to humans.

Depending on the formulation of a product it may contain other active and beneficial ingredients. This similar to hemp seed oil which contains omega fatty acids, amino acids, vitamins, minerals and other compounds that are beneficial.

The Differences Between Hemp and Marijuana?

Is high in the psychoactive compound THC, or delta-9 tetrahydrocannabinol, the compound in marijuana that causes a high.

Marijuana is rightly considered to be a “drug.” It is cultivated mainly for medicinal and “recreational” purposes. Indica and sativa strains, as well as hybrids of the two, are used to produce marijuana.

The United States federal government considers marijuana to be a Class I controlled substance. However, many U.S. states have instituted legislation to regulate its cultivation and allow its use as medicine. Some states have also legalized marijuana for recreational use.

Is not marijuana. Although hemp does contain some cannabinoids, it has negligible amounts of THC. In fact, in order to be legally cultivated, industrial hemp must contain less than 0.3% THC. Industrial hemp is grown for food and fibers. It contains relatively small concentrations of cannabinoids and terpenes and is not the most desirable source of CBD oil.

While many of the CBD products on the market are produced from industrial hemp, the CBD oil in our products is made from a CBD-rich cannabis sativa strain known as PCR hemp. PCR is short for phytocannabinoid rich — it contains as much as ten times the concentration of CBD as generic industrial hemp and negligible amounts of THC. It does not cause a high, and is therefore not considered a drug.

The Cannabis Plant

Hemp PlantCannabis is one of a genus of plants known as “Cannabaceae”. There are two main species of cannabis that are cultivated for human consumption, namely Cannabis indica, and Cannabis sativa.

Sativa plants are taller and produce more fiber and are therefore the species from which hemp cultivation arose. Indica plants are shorter and bushier and less suitable for farming for either industrial purposes or for production of food, but well suited for producing medical marijuana.

Sativa plants are taller and produce more fiber and are therefore the species from which hemp cultivation arose. Indica plants are shorter and bushier and less suitable for farming for either industrial purposes or for production of food, but well suited for producing medical marijuana.

What Are Cannabinoids?

Cannabinoids are active compounds produced by all cannabis plants. They account for most of the health benefits of cannabis. Cannabinoids found in plants are technically called phytocannabinoids.

Phytocannabinoids mimic compounds, which we call endocannabinoids that are produced naturally by all mammals.

  • Phytocannabinoids — Cannabinoids produced by plants
  • Endocannabinoids — Cannabinoids produced by the human body

Other cannabinoids found in PCR hemp include cannabichromene (CBC) and cannabigerol (CBG). Cannabichromene (CBC) is the third most common cannabinoid found in cannabis. Like CBD, cannabichromene is non-psychoactive.

Cannabigerol (CBG) is produced early on in the hemp’s growth cycle. Both CBC and CBG are believed to have properties similar to those of CBD.


Endocannabinoids, those produced naturally by our bodies, are signaling molecules. They are technically called neurotransmitters. Hormones are a more familiar type of neurotransmitter. A vast array of neurotransmitters is produced by the nervous system in response to various states of health and also environmental factors. They interact with receptors found on the surface of cells throughout our bodies. Their job is to instruct a cell to adjust its activities. This can include changing how cells react to other neurotransmitters.

The Human Endocannabinoid System (ECS)

Now we understand neurotransmitters work to adjust our cellular activity, let’s take a look at the role of cannabinoids in particular and their role in maintaining homeostasis — a state of balance, within the body.

The human endocannabinoid system (ECS) has two components. First is the endocannabinoid receptors found on the surface of cells throughout the body. Second is the endocannabinoids themselves that interact with those receptors.

For an example, CBD is known to mimic a signaling molecule called anandamide. Anandamide is responsible for the production and uptake of serotonin. Serotonin is often referred to as the “bliss molecule” because levels of serotonin in the body are directly associated with mood. Serotonin is the neurotransmitter which is responsible for “runner’s high.” Serotonin levels are often low in people suffering from depression and anxiety. Supplementation with CBD has been shown to raise serotonin levels.

The endocannabinoid system is vast and far-reaching. It regulates a wide array of bodily functions, from appetite regulation to sleep patterns, moods, metabolism, immune response, the lifespan of cells and much more. This is the reason that CBD seems to affect such a wide range of conditions.

Research Into CBD’s Therapeutic Benefits

In just over a half-century, cannabinoids have gone from obscurity to one of the most researched families of compounds in the world.

Female DoctorThe secrets of cannabinoids are vast and they run deep. After many years of study, still very little is known about how cannabinoids interact with the endocannabinoid system as well as other complex organs and systems in our bodies such as the immune system, the nervous system, the endocrine system, the cardiovascular system, the digestive system, the heart, liver, kidneys and the epidermis.

But one thing is certain — CBD does have an effect on all of these complex systems which themselves are not fully understood. Determining the exact mechanisms that are producing CBD’s vast array of effects might take many more decades. In the meantime, much research is underway, and many studies about CBD’s effects on the human body have already been published.